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May 21, 2019 by Jessica Pratt, EXCELLENCE Editor

Psychiatric Medication Discontinuation and Reduction study data now freely available

The dataset for the Psychiatric Medication Discontinuation and Reduction Study is now freely available through Open ICPSR (Inter-university Consortium for Political and Social Research)

The latest article drawing on the study data was published yesterday in Psychosis, An exploratory analysis of the role of social supports in psychiatric medication discontinuation: Results related to family involvement, authored by Laysha Ostrow, Bevin Croft, Anne Weaver, and Sarah Naeger.

Live & Learn, Inc. explains:
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April 12, 2019 by Jessica Pratt, EXCELLENCE Editor

Study of Micronutrients for Bipolar Disorder Seeking Additional Participants, Funding

BANGOR, Maine – A cutting edge study on the effect of micronutrients as a supporting treatment for bipolar disorder is currently underway in Bangor, Maine, led by Lewis Mehl-Madrona, MD, at Northern Light Family Medicine and Residency.

“The purpose of this trial is to determine whether a 36-ingredient micronutrient supplement (primarily vitamins and minerals) and fish oil (omega-3 fatty acid) supplement improves nutritional status and allows lower doses of conventional medications to be effective for bipolar disorder with fewer side effects, when studied under randomized and fully blinded conditions and compared to a placebo.

A follow-up open label phase will allow all participants, including those previously taking the placebo, to try the active micronutrient treatment for an additional twelve months.

Additional Participants Needed

The objective of this study is to assess the effectiveness of a micronutrient supplement + fish oil compared with placebo. To achieve this, the study needs a total of one hundred subjects who complete the first twelve months of the study. The prevalence of this disorder in the general population is only 3% and it has been difficult to recruit sufficient subjects. Researchers need to recruit and enroll an additional fifty people in the study. All participants must live in the vicinity of Bangor, Maine. Those interested in enrolling in the study should contact Edwina at 207.973.9013.

Additional Funding for Open Label Phase Needed

Once the study participants complete the first twelve months of the randomized study they will transition onto the open label phase of the study. This is less intensive but will still involve quarterly check in, data collected and the micronutrient supplement + fish oil dispensed to participants by the researchers.

Our hypothesis is the micronutrients and fish oil improves nutritional status and as we do not know the nutritional baseline of participants at the start the study, the longer we can follow the participants the better we will be able to understand the impact of taking this dose of vitamins over time. To achieve this we will need an additional $25,000 so the participants can check in quarterly, the data collected and the analysis completed.

The study was first made possible by a generous donor to Dr. Bonnie Kaplan’s Nutrition & Mental Health Research Fund at the Foundation for Excellence in Mental Health Care.

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April 9, 2019 by Psychiatric News Alert | APA

Recurrent Phone Call Intervention May Reduce Suicidality in Adolescents Following Hospitalization

(Psychiatric News) – Adolescents who have been hospitalized for suicidal behaviors may benefit from recurrent follow-up calls following hospital discharge, according to a report in Psychiatric Services.

Compared with adolescents receiving a single post-discharge call, adolescents receiving recurrent phone calls had a significantly lower rate of suicidal behavior and greater confidence in their suicide safety plan.

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February 13, 2019 by Jessica Pratt, EXCELLENCE Editor

Excellence Awards 2019 Open Dialogue Grant

The new project will be coordinated by the Institute of Cognitive Science and Technology of the Italian National Research Council and realized in collaboration with an international team of Open Dialogue researchers. 

 The Foundation for Excellence in Mental Health Care would like to congratulate the research team coordinated by Drs. Raffaella Pocobello (ISTC-CNR) and Giuseppe Salamina (ASL-TO) who will conduct the Expanding the Science and Practice of Open Dialogue: An international collaborative multicenter research project to evaluate the effectiveness of Open Dialogue in various mental health care contexts around the world. 

The Open Dialogue approach to early psychosis is contrasted to the standard practice of immediate diagnosis and prescribing antipsychotic medication for people experiencing early psychosis. While Open Dialogue is growing in practice around the world and shows great promise, studies worldwide are limited and lack systematic application across settings.

This new project, based on an international collaborative process, will produce consistent documentation of Open Dialogue practices across study sites and further our understanding of the challenges and successes of improving the quality of Open Dialogue practice, in particular, how Open Dialogue practices can be advanced in such a way that they are implemented with fidelity to the evidence as they are adapted for local contexts and cultures.

This grant will fund the preparatory phase (year 1) of a three-part work plan. Funds are currently being raised to support year two’s pilot phase and the subsequent main study phase.

Basic Tenets of Open Dialogue
Open Dialogue is one of the most promising approaches for mental health care. It is a family/personal network approach based on the following principles:

  • provision of immediate help
  • social network perspective
  • flexibility and mobility of treatment
  • responsibility
  • psychological continuity
  • tolerance of uncertainty
  • dialogue and polyphony

EXCELLENCE is an international mental health community foundation which matches private philanthropy to independent research projects and innovative programs that lead to recovery. Our team of donors and volunteers embodies a rich diversity of knowledge and expertise including people with lived experience of our current system of care, family members, psychiatrists and other clinical professionals, researchers, and philanthropists. EXCELLENCE strives to nurture scientific excellence and innovation in mental health research and program support by supporting scientific rigor, trauma-informed care, informed consent, peer support and recovery-based initiatives.

Principle investigators can be reached at Guiseppe Salamina giuseppe.salamina@aslcittaditorino.it and Raffaella Pocobello raffaella.pocobello@istc.cnr.it.

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January 8, 2019 by Malcom Gladwell | The New Yorker Magazine

Is Marijuana as Safe as We Think?

Permitting pot is one thing; promoting its use is another.

 

(The New Yorker Magazine) – A few years ago, the National Academy of Medicine convened a panel of sixteen leading medical experts to analyze the scientific literature on cannabis. The report they prepared, which came out in January of 2017, runs to four hundred and sixty-eight pages. It contains no bombshells or surprises, which perhaps explains why it went largely unnoticed. It simply stated, over and over again, that a drug North Americans have become enthusiastic about remains a mystery.

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November 19, 2018 by Jessica Pratt, EXCELLENCE Editor

Request for Proposal: Expanding the Science and Practice of Open Dialogue

Expanding the Science and Practice of Open Dialogue: An international collaborative multicenter research project to evaluate the effectiveness of Open Dialogue in various mental health care contexts around the world. Applications due January 2, 2019.

Overview

The Foundation for Excellence in Mental Health Care is pleased to announce this funding opportunity, Expanding the Science and Practice of Open Dialogue: An international collaborative multicenter research project to evaluate the effectiveness of Open Dialogue in various mental health care contexts around the world.  This funding opportunity provides for one multi-year award to a single eligible applicant, with the possibility to be renewed annually.

Purpose of award: The Foundation for Excellence in Mental Health Care (EXCELLENCE) is interested in funding a visionary, international research project that will lead to consistent documentation of Open Dialogue practices across study sites, as well as understanding challenges and successes to improve the quality of Open Dialogue practice. Applicants should propose to evaluate Open Dialogue practices in countries including those outside the United States, and be prepared to work with EXCELLENCE to advance our understanding of how Open Dialogue practices can be advanced in such a way that they are implemented with fidelity to the evidence while also being adapted for local contexts and cultures. The Open Dialogue approach to early psychosis is contrasted to the standard practice of immediate diagnosis and prescribing antipsychotic medication for people experiencing early psychosis. While Open Dialogue is growing in practice around the world and shows immense promise, studies worldwide are limited and lack systematic application across settings.

Download Full RFP (pdf)

 

 

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November 6, 2018 by David Healy, MD | DavidHealy.org

The Goetzsche Affair

(DavidHealy.org) – In recent years, under Amar Jesani, the Indian Journal of Medical Ethics has emerged as one of the few venues willing to engage with pressing bioethical issues without fear of whether pharmaceutical companies or governments might be offended.

Amar approached me a week ago to comment on the Goetzsche Affair.  I borrowed a phrase invented by Tim Moss – Evidence Debased Medicine – for the purpose.  A PDF of the article complete with references can be accessed Here.  The body of the article is below.


The first articles by Iain Chalmers announcing the Cochrane Collaboration appeared in 1992 (1), whose mission would be to systematically review medical evidence with a view to producing the best quality and trustworthy evidence (2). Writing The Antidepressant Era in 1995, I characterised systematic reviews as a logical, and necessary medical development (3). Although the founders came from Canada (Sackett and Enkin), the United States (Dickersin), Denmark (Gøtzsche) and elsewhere, from the mid-1990s, the United Kingdom (UK) became the home of the Collaboration.

The idea of embodying Evidence Based Medicine (EBM) in Guidelines also took shape at this time. In Britain, in 1997, a Labour government created a National Institute for Clinical Excellence (NICE) which began issuing Guidelines underpinned by Cochrane methods and in some instances with Cochrane collaboration. The NICE process was and still is highly regarded, sufficiently so for the Labour government to issue a new plan for Britain’s National Health Service (NHS) that on the basis of newly-minted standards of care set about standardising the health service in a manner that embraces continuity of data, with an interchangeability of personnel, rather than continuity of care (4).

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October 19, 2018 by Jessica Pratt, EXCELLENCE Editor

Foundation for Excellence in Mental Health Care Welcomes Laysha Ostrow and Ro Speight to its Board of Directors

The Excellence Board of Directors today welcomed new members Laysha Ostrow and Ro Speight at its annual retreat in Wilsonville

Ro Speight, NY-CPS

(Wilsonville, OR) – Ronda “Ro” Speight, New York Certified Peer Specialist, is committed to pioneering the advancement of Professional Peer Support in the mental health field. Specifically, helping to define what are “collaborative practices” between peer professionals and traditional mental health professions. Ro has been trained in various peer professional and progressive clinical methodologies, which benefit from integrating the peer professional perspective.

In the interest of this commitment, she has been trained in Social Networking, derived from Open Dialogue, currently aiming to utilize the strengths of both clinical and peer facilitation in the United States. Ro is trained as a Hearing Voices Network Facilitator, which is transforming traditional stigmas and perspectives of voice hearing and other alternative sensory phenomena. She is currently working as a Peer and Recovery Specialist at Mental Health Association (MHA) of Westchester, New York. MHA programs include On Track New York, a comprehensive program for young individuals experiencing first-episode psychosis and the Westchester Recovery Network, a peer-directed in-community peer support program.

Ro is also active in the larger New York community, modeling and applying peer professional competencies in traditional medical model settings. She is currently supporting the peer professional presence at New York Presbyterian Hospital- Westchester Division, developing comprehensive Peer Professional led wellness groups on inpatient units. Ro is enjoying being an agent of positive change after years of trying to personally navigate her identity and purpose through a complicated mental health system.

Laysha Ostrow, PhD

Laysha Ostrow is the founder and CEO of Live & Learn, Inc., a California-based, consumer-run and woman-owned social enterprise that provides research, technical assistance, and knowledge translation services to behavioral health system stakeholders. She is also an Adjunct Professor in the School of Community and Global Health at Claremont Graduate University and holds a PhD from the Johns Hopkins School of Public Health and a Master of Public Policy from the Heller School for Social Policy and Management at Brandeis University. Laysha completed a Postdoctoral Research Fellowship in the Department of Psychiatry at UCSF and maintains a position there as a Visiting Professional.

She has been an invited speaker at the Carter Center Symposium, the Kennedy Forum on Mental Health, the U.S. Senate HELP Committee’s roundtable to reauthorize the Higher Education Act, and the California Health Facilities Financing Authority. In 2016, Laysha was the recipient of the 2016 Carol T. Mowbray Early Career Research Award from the Psychiatric Rehabilitation Association.

As a person who experienced mental health systems that are often ineffective at promoting recovery and community inclusion, she is passionate about improving these systems through research that advances the use of evidence-based practices in real-world settings.

 

 

 

 

 

 

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October 17, 2018 by Jessica Pratt, EXCELLENCE Editor

C.O.P.E. Policy Pressure Group Strives To Better Safeguard Young Children From Prescribed Psychiatric Drugs

(MadInAmerica.com) – From The British Psychological Society: “C.O.P.E. [Campaign against the Over-prescription of Psychiatric drugs in Education] is a group of child mental health professionals…[whose] primary aim is to change public policy in key areas of child and adolescent mental health…an attempt to initiate this change was made as part of the consultation process for the new NICE [National Institute for Health and Care Excellence] Guidelines.

The BPS requested that NICE should consider recommending a ban on medicating children with psycho-stimulants who are under the age of five years old…Our C.O.P.E. mission statement clearly articulates our collective beliefs well and includes this area of policy:

We share the view that a caring and morally mindful society must better safeguard children by allowing them to develop their unique personalities and behaviours without a first response to prescribe psychiatric drugs for their behavioural difficulties.

We especially believe that children under the age of five should not be prescribed psychiatric drugs if their behaviour is the only concern.

Please help us to better safeguard children, which is our shared primary duty, and challenge the inappropriate use of psychiatric drugs in the young by signing the petition and supporting our objectives through professional discussions in mental health teams and childrens’ services.”

Source: Madinamerica.com/2018/10/c-o-p-e-strives-better-safeguard-children/

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October 17, 2018 by Pauline Anderson | Medscape

Schizophrenia in Youth Not a Neurodegenerative Illness

(Medscape) – Young patients with recent-onset schizophrenia do not show signs of cognitive deterioration or disruption of ongoing brain development in the first years following illness onset, new research shows.

Results of a large longitudinal study show that young patients with schizophrenia experience cognitive impairment prior to the onset of psychotic symptoms, but the trajectory of their neurobehavioral development and performance is comparable to that of healthy control persons.

“The study results suggest that whatever effect cognition has in schizophrenia seems to happen before people develop clinical symptoms, the psychotic symptoms,” study investigator Cameron S. Carter, MD, professor of psychiatry and psychology, and director of the Schizophrenia Research and Education Program, Department of Psychiatry and Behavioural Sciences, University of California, Davis, told Medscape Medical News.

“So cognitive dysfunction is already there when people come in for treatment,” he said.

The findings are in line with the neurodevelopmental model of schizophrenia. This model hypothesizes that prenatal central nervous system insultsand/or genetic alterations during early brain developmentinteract with environmental risk factors and lead to the onset of psychosis in late adolescence or early adulthood.

“The study confirms our sense that schizophrenia is not a neurodegenerative disorder; the brain does not necessarily deteriorate after people become ill and develop these symptoms,” said Carter.

“In fact, these young people have the capacity to continue to improve and develop to the same degree as typical individuals,” he said.

The study was published online October 3 in JAMA Psychiatry.

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